Damian Tyler
Additional Fellow and Tutor in Medicine; Professor of Physiological Metabolism; British Heart Foundation Senior Research Fellow; Director of MR Physics at the Oxford Centre for Clinical Magnetic Resonance Research (OCMR)Based in Oxford since 2011, I am currently the Director of MR Physics at the Oxford Centre for Clinical Magnetic Resonance Research (OCMR), a British Heart Foundation Senior Research Fellow and an Additional Fellow at Somerville College.
Since arriving in Oxford in 2001, I have acquired more than 20 years’ experience in the development and application of Magnetic Resonance Imaging and Spectroscopy (MRI/MRS). I gained my MSci in Medical Physics in 1998 and my doctorate in 2001, both from the University of Nottingham. I am an associate member of the Cardiac Metabolism Research Group (CMRG) and leads the Oxford Metabolic Imaging Group.
My research in Oxford has been based on the study of cardiac structure, function and metabolism in normal and diseased hearts using MRI/MRS. This has included developing techniques using high spatial and temporal resolution CINE imaging to assess heart function and localized phosphorus and carbon spectroscopy to monitor and investigate abnormalities of metabolism. More recently, I have been awarded a British Heart Foundation Senior Research Fellowship to develop the technique of hyperpolarized magnetic resonance imaging (HP-MRI) for application to the study of cardiac metabolism in the human heart. A fundamental limitation of magnetic resonance is its low sensitivity, but the recently developed technique of HP-MRI provides a practical method to gain up to 10,000-fold increases in sensitivity in molecules with an in vivo stability of approximately one minute. This has enabled visualization of 13C-labelled cellular metabolites in vivo and, more importantly, their enzymatic transformation into other species. Using this novel approach, we have recently published the world’s first demonstration of the use of HP-MRI to assess metabolic changes in the diabetic (doi: 10.1161/CIRCRESAHA.119.316260) and ischaemic human heart (doi: 10.1016/j.jcmg.2020.12.023).
The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.
Journal article
Schroeder MA. et al, (2012), Circ Cardiovasc Imaging, 5, 201 – 209
Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease.
Journal article
Schroeder MA. et al, (2011), Circulation, 124, 1580 – 1594
Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study.
Journal article
Atherton HJ. et al, (2011), Circulation, 123, 2552 – 2561
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
Journal article
Schroeder MA. et al, (2009), FASEB J, 23, 2529 – 2538
In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance.
Journal article
Schroeder MA. et al, (2008), Proc Natl Acad Sci U S A, 105, 12051 – 12056
Mar Umbert-Kimura
Chapel and Music AdministratorJudith Unwin OBE FRSA
Distinguished Friend of SomervilleJudith Unwin read Philosophy Politics & Economics at Somerville College and subsequently spent 35+ years in international banking in the City.
She initially joined the merchant bank Lazard Brothers & Co., Limited as their first female graduate trainee and worked in the Bank’s International Division arranging financing for infrastructure projects in a range of overseas markets. Having first visited India in 1984 she has been a regular and frequent visitor ever since.
After 10 years at Lazard Judith joined ANZ Grindlays Bank in London specialising in South Asia, particularly India. She was appointed to various UK Government advisory positions including the South Asia Advisory Group under the auspices of the then Department of Trade & Industry and participated in many Ministerial Trade Missions to India.
From 2000 she held a number of senior roles at BNP Paribas London the last being head of a team working with the international Development Finance Institutions and Multilateral Agencies. She was a founding member of the Indo British Partnership and subsequently Director and Chair of the Nominations Committee of the UK India Business Council (2008-2014). She took a sabbatical from the Bank in 2006 to travel to rural India researching and working with women’s self help groups and microfinance schemes and has supported several Indian charities.
In parallel with her professional career, Judith has held a number of Non Executive Director and pro bono trustee roles.
She retired from banking in 2016 and is the Vice Chair of The Prison Phoenix Trust and a trustee of Music at Oxford.
Judith was awarded an OBE in 2000 for Services to Export promotion to South Asia.
Baroness Vadera of Holland Park
Honorary FellowIn 2014 Baroness Vadera was appointed as the first woman to chair a major UK bank.
Her move to Santander follows a remarkable career that has seen her at the heart of banking, business and politics in the UK and abroad. We asked her about the global financial crisis, trouble in the Eurozone, the outlook for women in the workplace and the lessons she learnt from an exceptional childhood.
Gladson Vaghela
Welfare OfficerHello there, I’m Gladson Vaghela, and I’m delighted to serve as your MCR Welfare Officer. I’m currently reading for my MSc in Global Health Science and Epidemiology.
In my capacity as Welfare Officer, I’m dedicated to being your ally in navigating the challenges that may arise during your time at university. Whether it’s a health-related concern, a mental well-being issue, or if you just need someone to talk to, I’m here to provide a listening ear and guide you to the appropriate resources. Think of me as your personal signpost, directing you to the vast support network we have, from counselling services to health centres and all essential support groups. Additionally, I come from a background in medicine, which I hope brings an added layer of understanding and empathy to our interactions.
Reaching out for help can sometimes feel daunting—trust me, I’ve been there. But please know that I am always happy to hear from you, and confidentiality is a cornerstone of our interactions. Remember, no problem is too big or too small. University life is a journey with its fair share of ups and downs, and seeking help is a sign of strength, not weakness.
So whether you need assistance or simply fancy a chat over a cup of coffee, my offer stands—don’t hesitate to reach out. Let’s create an inclusive and supportive community where each one of us can truly thrive.
Renier van der Hoorn
Senior Research Fellow; Associate Professor of Plant SciencesRenier is a plant biologist interested in understanding the manipulation of plants by microbial plant pathogens.
His research activities also aim at improved recombinant glycoprotein production in plants and pioneering activity-based proteomics in plant science.
Renier was born in Leiden, the Netherlands in 1971 and was fascinated by plant biology from early childhood. He studied chemistry at Leiden University and focused soon on plant molecular biology and biochemistry. After his graduation in 1996, he started his PhD in Molecular Phytopathology (Wageningen University, Prof. Dr. Pierre de Wit), where he worked on the tomato Cf resistance proteins.
He continued working on Cf proteins in Wageningen as a postdoc, and started his own research program by introducing and applying activity-based protein profiling in plants. To further develop the technology he joined the phosphoproteomics group of Dr. Scott Peck for one year (Sainsbury lab, John Innes Centre, Norwich, UK).
He initiated the Plant Chemetics lab in October 2005 at the Max Planck Institutes of Cologne and Dortmund as part of the Chemical Genomics Centre of the Max Planck Society. His research group operated independently from the departments at the Max Planck Institutes while he trained twelve MSc students, nine PhD students, eleven postdocs and over 30 visiting scientists.
In October 2013, he was appointed Associate Professor at the Department of Plant Sciences of the University of Oxford, and elected Tutor in Plant Sciences at Somerville College. His research focuses on the use of chemical proteomics to uncover novel host manipulation mechanisms employed by microbes when colonizing the apoplast.
https://scholar.google.co.uk/citations?user=6UPEEfUAAAAJ&hl=en&oi=ao
Ilyas, M., Hörger, A. C., Bozkurt, T. O., Van den Burg, H. A., Kaschani, F., Kaiser, M., Belhaj, K., Smoker, M., Joosten, M. H. A. J., Kamoun, S., and Van der Hoorn, R. A. L. (2015) Functional divergence of two secreted immune proteases of tomato. Current Biol. 25, 1-7.
Lu, H., Chandrasekar, B., Oeljeklaus, J., Misas-Villamil, J. C., Wang, Z., Shindo, T., Bogyo, M., Kaiser, M., and Van der Hoorn, R. A. L. (2015) Subfamily-specific probes for Cys proteases display dynamic protease activities during seed germination. Plant Physiol. 168, 1462-1475.
Dong, S., Stam, R., Cano, L. M., Song, J., Sklenar, J., Yoshida, K., Bozkurt, T. O., Oliva, R., Liu, Z., Tian, M., Win, J., Banfield, M. J., Jones, A. M., Van der Hoorn, R. A. L., and Kamoun, S.(2014) Effector specialization in a lineage of the Irish potato famine pathogen. Science 343, 552-555.
Chandrasekar, B., Colby, T., Emon, A. E. K., Jiang, J., Hong, T. N., Villamor, J. G., Harzen, A., Overkleeft, H. S., and Van der Hoorn, R. A. L. (2014) Broad range glycosidase activity profiling. Mol. Cell. Proteomics. 13, 2787-2800.
Sueldo, D., Ahmed, A., Misas-Villamil, J. C., Colby, T., Tameling, W., Joosten, M. H. A. J., andVan der Hoorn, R. A. L. (2014) Dynamic hydrolase activities precede hypersensitive tissue collapse in tomato seedlings. New Phytologist 203, 913-925.
Angela Vincent
Emeritus FellowProfessor Vincent’s (FRS FMedSci) major research interest is in the role of autoimmunity in neurological diseases, mainly auto-antibody mediated ion channel and receptor disorders.
These rare conditions are now recognised world-wide, diagnosed with tests she helped to develop, and treated with drugs that reduce the levels of the antibodies, with very good clinical responses.
She was previously honorary consultant in immunology and founded the Oxford Clinical Neuroimmunology service, an international referral centre for the measurement of antibodies in neurological diseases, that she led for 24 years. She was formerly Head of Department of Clinical Neurology (2005-2008), President of the International Society of Neuroimmunology (2001-2004), and an Associate Editor of the journal Brain (2004-2013). She formally retired in 2016 but has continued to publish with collaborators in the UK and abroad (total >400). She has received many national and international awards for her work.
Selected key publications
Vincent A A. Immunology of acetylcholine receptors in relation to myasthenia gravis. Physiological reviews. 1980 60:756-824.
Vincent A. Unravelling the pathogenesis of myasthenia gravis. Nature reviews Immunology. 2002 2:797-804.
Hoch W, …….Vincent A. 2001. Autoantibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat Med 7: 365-368.
Vincent A et al. Association of Leucine-Rich Glioma Inactivated Protein 1, Contactin-Associated Protein 2, and Contactin 2 Antibodies With Clinical Features and Patient-Reported Pain in Acquired Neuromyotonia. JAMA Neurol. 2018;75:1519-1527
Vincent A et al. Arthrogryposis Multiplex Congenita with Maternal Autoantibodies Specific for a Fetal Antigen. Lancet. 1995;346:24-5.
Coutinho E…….Vincent A. Persistent microglial activation and synaptic loss with behavioral abnormalities in mouse offspring exposed to CASPR2-antibodies in utero. Acta Neuropathol. 2017;134:567-583.
Coutinho E……… Vincent A. Inhibition of Maternal-to-Fetal Transfer of IgG Antibodies by FcRn Blockade in a Mouse Model of Arthrogryposis Multiplex Congenita. Neurol Neuroimmunol Neuroinflamm. 2021;8:e1011.
Vincent A et al. Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis. Brain 2004;127:701-712.
Irani SR…………..Vincent A. Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia. Brain;2010;133:2734-48.
Konstantina Vogiatzaki
Fellow & Tutor in Engineering; Associate Professor of Engineering ScienceKonstantina works in the field of fluid dynamics. She has extensive teaching and research experience in simulation approaches – based on Computational Fluid Dynamics (CFD) and more recently Machine Learning (ML) – that support the virtual design of low-carbon footprint propulsion and energy systems.
She has also extended her research towards applying the numerical approaches she develops to the biomedical field (lung modelling and cryosurgery).
She graduated from the Department of Applied Mathematics at the National Technical University of Athens (NTUA) in 2005, and obtained her PhD from Imperial College London (2010) with a thesis entitled “Stochastic and deterministic multiple mapping conditioning for jet flames”. She was awarded the prestigious Bernard Lewis Fellowship by the Combustion Institute in 2010 for the development of a novel turbulent combustion modelling framework (namely Multiple Mapping Conditioning, MMC).
Following her PhD she worked as a Post-Doctoral Researcher at Imperial College London for two years, developing LES models for sprays in gas turbines, before moving to the Massachusetts Institute of Technology (MIT), where she was appointed as a Research Scientist at the Mechanical Engineering Department for two years, and she led lead the CFD team of the MIT’s Reacting Gas Dynamics Laboratory. working towards developing numerical tools for the modelling of combustion instabilities and fluid mixing for hydrogen fuelled systems. She conducted academic research and teaching in different institutions in the UK and abroad including the University of Stuttgart, Imperial College, City University of London and University of Brighton, after which she joined King’s College London as a Senior Lecturer (Associate Professor) and an EPSRC-UKRI Innovation Fellow.
Konstantina’s research is at the forefront of fluid dynamics with more than 60 high impact peer reviewed articles. Recent papers have been selected as editor’s pick and featured as journal covers in various journals such as Physics of Fluids. She has been involved in various projects with industrial support and was also awarded the prestigious “Hinshelwood Prize” in 2012 which recognises meritorious work by a young member of the British Section of the Combustion Institute.
Konstantina trained as both an engineer and a mathematician and her research is at the crossroads between Mathematics, Engineering and Complex Systems, covering both applications and fundamentals. Particular emphasis in their research is given to fluid dynamics at extreme pressure and temperature conditions such as cryogenic fluids, flammable fluids and supercritical fluids.
Latest Research
Richard Vowell
Deputy Catering & Conference ManagerRoman Walczak
Senior Research FellowI arrived in the UK in 1993 to take my fellowship in Somerville and lectureship in the Physics Department. The UK is my fourth country after my native Poland, Switzerland and Germany where I lived and worked for many years; quite a long journey from state schools in Poland to Oxford. In 2019 I retired my Tutorial Fellowship to become a Senior Research Fellow.
Most of my research so far has been in experimental particle physics but in recent years I have been moving my main interests from particle to accelerator physics. In plasma (ionised gas, for example hydrogen), using a laser, one can move electrons away from ions creating a huge electric field; many orders of magnitude bigger then what one can get using current technology. Such a field can be used to accelerate particles and to build accelerators beyond the Large Hadron Collider era and beyond current X ray sources (synchrotron radiation), like Diamond near Oxford. Acceleration using plasma would move particle physics to a new territory and simultaneously would make tuneable wavelength, short pulse X ray sources affordable for Universities and hospitals.
My main expertise in particle physics is in the design of wire chambers and calorimeters and on physics beyond the Standard Model as well as on some aspects of Quantum Chromo Dynamics. I worked at the following accelerators: CERN: PS, ISR, SPS; and DESY: PETRA, HERA. At John Adams Institute for Accelerator Science at Oxford University, I am leading the Lasers for Accelerators (L4A) group.
Besides physics, I am working on a small family farm and I am a keen swimmer; I am holding one national swimming record in my age group.
My advice to my students: Only beginners compete. When you go to a higher level, your aim is quality.
‘Guiding of high-intensity laser pulses in 100mm-long hydrodynamic optical-field-ionized plasma channels’
A Picksley, A Alejo, J Cowley, N Bourgeois, L Corner, L Feder, J Holloway, H Jones, J Jonnerby, Hm Milchberg, Lr Reid, Aj Ross, R Walczak, Sm Hooker
Physical Review Accelerators and Beams American Physical Society 23:8 (2020) 081303
Numerical modelling of chromatic effects on axicon-focused beams used to generate HOFI plasma channels
Aimee Ross, Aaron Alejo, Alexander von Boetticher, James Cowley, James Holloway, Jakob Jonnerby, Alexander Picksley, Roman Walczak, Simon Hooker
Journal of Physics: Conference Series IOP Publishing 1596 (2020)
Eupraxia, a step toward a plasma-wakefield based accelerator with high beam quality
D Alesini, A Aschikhin, A Beck, M Chen, E Chiadroni, M Croia, B Cros, A Del Dotto, M Ferrario, RA Fonseca, LA Gizzi, SM Hooker, L Labate, A Martinez De La Ossa, A Mosnier, A Mostacci, D Oumbarek Espinos, A Stella, EN Svystun, D Terzani, P Tomassini, JM Vieira, CP Welsch, SM Wiggins, J Wolfenden
Journal of Physics: Conference Series IOP Science 1350:1 (2019)
Status of the Horizon 2020 EuPRAXIA conceptual design study
G Fiore, RA Fonseca, M Galimberti, A Gallo, A Ghaith, D Giove, A Giribono, LA Gizzi, FJ Grüner, AF Habib, C Haefner, T Heinemann, B Hidding, BJ Holzer, SM Hooker, T Hosokai, M Huebner, A Irman, FJ Jafarinia, DA Jaroszynski, C Joshi, M Kaluza, M Kando, OS Karger, E Khazanov
Journal of Physics: Conference Series 1350:1 (2019)
Laser-driven high-quality positron sources as possible injectors for plasma-based accelerators
A Alejo, Roman Walczak, G Sarri
Scientific Reports Nature Research 9:1 (2019) 5279
Timothy Walker
Senior Stipendiary Lecturer in Plant Sciences; Former Director of the University of Oxford Botanic Garden and Harcourt ArboretumI teach Biology at Somerville, and most of my teaching concerns plant biology because this is the interesting part of the subject.
In the first year the topics I cover include plant life histories including pollination, biological classification, the use of plants in medicine, the emergence of agriculture, and conservation. In the second year I teach about plant adaptations (particularly those found in Mediterranean-type regions), ecology, and ethnobotany. In the final year I run an option on species conservation and I teach on the Tenerife Field Trip.
Prior to coming Somerville I worked at the Oxford Botanical Gardens and Harcourt Arboretum for the best part of 34 years, the last 26 as Horti Praefectus (i.e. director). My particular interests are plant conservation and the genus Euphorbia which is a fascinating group of 2000 species found all over the world.
Plant Conservation (2013) Timber Press
Plants – a very short introduction (2012) OUP
Euphorbias (2002) RHS
Wantoe T. Wantoe
Oxford Student Union RepresentativeMy name is Wantoe T. Wantoe, and I am from Liberia. I am currently an MSc candidate in Comparative and International Education at the Department of Education, University of Oxford. Previously, I completed a Master in Public Policy at the Blavatnik School of Government, Oxford.
I serve as the Oxford Student Union Representative for the Middle Common Room (MCR) at Somerville College, where I ensure inclusivity and advocate for the voices of Somerville students within the larger Oxford Student Union. My role focuses on fostering a supportive environment where diverse perspectives are valued, and students’ needs and concerns are effectively represented in university-wide decision-making.
Sam Warburton
Retaining Fee LecturerGeorge Ward
Mary Ewart Junior Research Fellow;I am a Junior Research Fellow at the University of Oxford.
My main research interests are in the ‘human side’ of the future of work, the emotional bases of political behavior, and the economic determinants of subjective wellbeing (or “happiness”).
My work has been published in various academic journals including the Review of Economics and Statistics, Journal of Personality and Social Psychology, and American Journal of Political Science. I am also passionate about science communication and public engagement, and have written about my research for various outlets including Harvard Business Review, VoxEU, The Conversation, SPSP Character & Context, The Hill, and UN World Happiness Report. My research has also been featured by news outlets including The Economist, Financial Times, BBC, CNN, The Atlantic, Business Insider, Newsweek, and The Guardian.
Research Papers
The Asymmetric Experience of Positive and Negative Economic Growth: Global Evidence Using Subjective Well-Being Data. Jan-Emmanuel De Neve, George Ward, Femke De Keulenaer, Bert Van Landeghem, Georgios Kavetsos, and Mike Norton. Review of Economics and Statistics, 2018, 100(2): 362–375
Happiness and Voting: Evidence from Four Decades of Elections in Europe. George Ward. American Journal of Political Science, 2020, 64(3): 504-518
(Un)Happiness and Voting in U.S. Presidential Elections. George Ward, Jan-Emmanuel De Neve, Lyle Ungar, and Johannes Eichstaedt. Journal of Personality and Social Psychology, 2021, 120(2), 370–383
Does Employee Happiness Have an Impact on Productivity? Clément Bellet, Jan-Emmanuel de Neve, and George Ward. Revise & Resubmit at Management Science
The Role of Negative Affect in Shaping Populist Support: Converging Evidence from the Field. George Ward, Andrew Schwartz, Salvatore Giorgi, Jochen Menges, and Sandra Matt. Reject & Resubmit at Journal of Personality and Social Psychology
Workplace Happiness and Employee Recruitment: Evidence From a Field Experiment. George Ward.
Work Centrality and the Relationship Between Stress and (Un)Happiness. George Ward, Hanne Collins, Mike Norton, and Ashley Whillans.
Book Chapters
What Makes for a Good Job? Evidence Using Subjective Wellbeing Data, in M. Rojas (Ed.), The Economics of Happiness, Springer, 2019, pp. 241-268
Happiness and Voting Behaviour. 2019, UN World Happiness Report.
Happiness at Work. 2017, UN World Happiness Report
Work and Wellbeing during COVID-19: Impact, Inequalities, Resilience, and the Future of Work. 2021, UN World Happiness Report
Jackie Watson
Alumni Relations ExecutiveStephen Weatherill
Senior Research FellowStephen Weatherill works on the constitutional, institutional and substantive law of the European Union.
He retired from the Jacques Delors Chair in European Law in 2021, and is now Professor Emeritus in the University and a Senior Research Fellow of the College.
His research interests embrace the field of European Law in its widest sense, although his published work is predominantly concerned with European Union trade law. . He is the author of LAW AND VALUES IN THE EUROPEAN UNION (Oxford University Press, 2016), PRINCIPLES AND PRACTICE IN EU SPORTS LAW (Oxford University Press, 2017), THE INTERNAL MARKET AS A LEGAL CONCEPT (Oxford University Press, 2017), CONTRACT LAW OF THE INTERNAL MARKET (Intersentia, 2017), EU CONSUMER LAW AND POLICY (Edward Elgar, 3rd edition, 2013), CASES AND MATERIALS ON EU LAW (Oxford University Press, 12th edition, 2016) and co-author of CONSUMER PROTECTION LAW (Ashgate Publishing, 2nd edition, 2005, with Geraint Howells), EUROPEAN ECONOMIC LAW (Dartmouth Publishing, 1997, with Hans Micklitz), and WEATHERILL AND BEAUMONT’s EU LAW (Penguin Books, 3rd edition,1999, with Paul Beaumont). The areas in which he has published papers in journals and edited collections in recent years include; the impact of subsidiarity in EU law; the involvement of the EU in private law; aspects of “flexible” integration in Europe; the elaboration of strategies for the management of the internal market; sport and the law; and the law and practice of product safety.
Borja Garcia, an Vermeersch and S R Weatherill, ‘‘A new horizon in European sports law: the application of the EU state aid rules meets the specific nature of sport’’ (2017) European Competition Journal
S R Weatherill, Principles and Practice in EU Sports Law (Oxford University Press 2017)
S R Weatherill, The internal market as a legal concept (OUP 2017)