Fay Probert

Dorothy Hodgkin Career Development Fellow

Fay graduated from Warwick University with a BSc in Mathematics before moving to the Department of Chemistry where she completed an MSc in Mathematical Biology and Biophysical Chemistry.

Since completing her PhD in Analytical Chemical Biology, Fay has worked at Bruker (UK) and the Medical Research Council (Harwell) applying analytical chemistry techniques, with a focus on NMR spectroscopy, to a range of biological and medical research questions. Throughout her postdoctoral career, Fay’s research has focused on using a multidisciplinary combination of analytical chemistry, mathematics, and biology techniques to understand the chemistry of small molecule pathways associated with disease. In particular, Fay is interested in better understanding the chemical processes associated with inflammation in the brain with the aim of improving the diagnosis and treatment of these diseases.

Fay joined the Department of Pharmacology at Oxford in October 2015 as a senior postdoctoral researcher in the Anthony lab managing a small team of metabolomics researchers and leading several projects which aim to develop NMR metabolomics and multivariate statistical methods to better diagnose, monitor, and predict treatment response in inflammatory diseases of the central nervous system. In 2018, Fay was awarded a Junior Research Fellowship at Somerville College, Oxford.

In 2021 Fay was a awarded a Dorothy Hodgkin Career Development Fellowship in the Chemistry Department. 

Fay has received research funding from the MS Society, MRC, EPSRC, BSRC, Merck, and Numares AG.

Publications

Foveal changes in AQP4-Ab seropositive NMOSD are independent of optic neuritis and not overtly progressive.
Journal article
Roca-Fernández A. et al, (2021), Eur J Neurol

Mom's diet matters: Maternal prebiotic intake in mice reduces anxiety and alters brain gene expression and the fecal microbiome in offspring.
Journal article
Hebert JC. et al, (2021), Brain Behav Immun, 91, 230 - 244

Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites.
Journal article
Chan SY. et al, (2020), Sci Rep, 10

A blood-based metabolomics test to distinguish relapsing-remitting and secondary progressive multiple sclerosis: addressing practical considerations for clinical application.
Journal article
Yeo T. et al, (2020), Sci Rep, 10

A single administration of the antibiotic, minocycline, reduces fear processing and improves implicit learning in healthy volunteers: analysis of the serum metabolome
Journal article
BURNET P. et al, (2020), Translational Psychiatry

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