Marion Schuller

Following my BSc and MSc in Pharmaceutical Sciences at the Ludwig Maximilian University, I obtained my DPhil in ‘Systems Approaches to Biomedical Science – Industrial Doctorate Centre’ at the University of Oxford under the supervision of Prof Stefan Knapp and Prof Benedikt Kessler in collaboration with Novartis. 

I investigated strategies to modify PARP14 function through macrodomain inhibition using a combination of biochemistry, structural biology and cell biology approaches. I joined the Ivan Ahel lab to pursue my interests in the development of inhibitors of ADP-ribosylation recognising modules and to study novel enzyme systems for the reversible ADP-ribosylation of DNA and their role in microbial pathogenicity.