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Professor Vanessa M. Ferreira

Associate Professor of Cardiovascular Medicine; Deputy Clinical Director, OCMR, JR Hospital Honorary Consultant Cardiologist; Lecturer in Cardiovascular Medicine
SB MD DPhil FRCPC
Division of Cardiovascular Medicine, Radcliffe Department of Medicine

Vanessa Ferreira specialises in myocardial tissue characterisation using quantitative cardiovascular magnetic resonance (CMR) techniques and advanced image analysis to extract the most meaningful clinical information for diagnostics and patient management.

  • Society for Cardiovascular Magnetic Resonance (SCMR), Board of Trustees
  • Fulford Junior Research Fellow, Somerville College (2014-2016)
  • Doctor of Philosophy (DPhil) Cardiovascular Medicine, University of Oxford, UK
  • Fellow, Royal College of Physicians of Canada (FRCPC)
  • Doctor of Medicine (MD), University of British Columbia, Vancouver, Canada
  • Bachelor of Science (SB), Biology, Massachusetts Institute of Technology, USA

 

Vanessa obtained a doctorate in Cardiovascular Medicine at the University of Oxford, which focused on cardiovascular magnetic resonance (CMR) myocardial tissue characterisation, converging with MR physics technical development towards clinical translation of myocardial T1-mapping.

Briefly, each tissue type in the body has a magnetic property called T1 relaxation time, which can be measured (in milliseconds) using MRI scans. The heart has a specific range of normal T1 values, deviation from which may be indicative of disease.

T1-mapping generates a pixel-by-pixel T1-map of the heart, which can locate small areas of disease in a numerical manner. Thus, T1-mapping provides a quantitative way to examine the heart, does not require any injection of contrast agents or radiation, and produces coloured MRI images which give additional information compared to traditional MRI images.

One of her goals is to advance CMR methods to gain more insight into heart disease in ways not previously possible, in a non-invasive way. Another is to minimise the need for injection of contrast agents for diagnostic images, allowing more patients to benefit from cardiac MRI, eliminating adverse reactions to contrast agents, and savings in time and cost.

Working with MR physicists, engineers, biomedical imaging experts and clinician-scientists from a range of specialties, Vanessa’s research at the OCMR is highly collaborative and interdisciplinary. Vanessa also delivers CMR education, and supervises DPhil, MSc and medical students in CMR research at the OCMR, based at the John Radcliffe Hospital.

 


Selected Publications

 

ORCID: 0000-0002-0046-7634

 

  1. Ferreira VM, Marcelino M, Piechnik SK, Marini C, Karamitsos TD, Ntusi NAB, Francis JM, Robson MD, Arnold JR, Mihai R, Thomas JD, Herincs M, Hassan-Smith ZK, Greiser A, Arlt W, Korbonits M, Karavitaki N, Grossman AB, Wass JA, Neubauer S. “Pheochromocytoma is Characterized By Catecholamine Myocarditis, Focal and Diffuse Fibrosis, and Persistent Subclinical Systolic and Diastolic Dysfunction”. Journal of American College of Cardiology 2016; 67(20):2364-2374. View full text.
  2. Liu A, Wijesurendra RS, Francis JM, Robson MD, Neubauer S, Piechnik SK, Ferreira VM. “Adenosine stress and rest T1-mapping can differentiate between ischemic, infarcted, remote and normal myocardium without the need for gadolinium contrast agents” JACC Cardiovasc Imaging Dec 9, 2015. View full text.
  3. VM Ferreira; SK Piechnik; E Dall’Armellina; TD Karamitsos; JM Francis; RP Choudhury; MG Friedrich; MD Robson; S Neubauer. Non-Contrast T1-Mapping Detects Acute Myocardial Edema with High Diagnostic Accuracy: A Comparison to T2-weighted Cardiovascular Magnetic Resonance Imaging. Journal of Cardiovascular Magnetic Resonance 2012, 14:42. View full text.
  4. VM Ferreira; SK Piechnik; E Dall’Armellina; TD Karamitsos; JM Francis; N. Ntusi; C. Holloway; RP Choudhury; A Kardos; MD Robson; MG Friedrich; S Neubauer.T1-mapping for the Diagnosis of Acute Myocarditis Using Cardiovascular Magnetic Resonance – Comparison to T2-weighted and Late Gadolinium Enhanced Imaging. JACC Cardiovasc Imaging. 2013 Oct;6(10):1048-58. View full text.
  5. VM Ferreira; SK Piechnik; E Dall’Armellina; TD Karamitsos; JM Francis; N. Ntusi; C. Holloway; RP Choudhury; A Kardos; MD Robson; MG Friedrich; S Neubauer. Native T1-mapping detects the location, extent and patterns of acute myocarditis without the need for gadolinium contrast agents. Journal of Cardiovascular Magnetic Resonance 2014, 16:36. View full text.
  6. Ferreira VM, Wijesurendra RS, Liu A, Greiser A, Casadei B, Robson MD, Neubauer S, Piechnik SK. “Systolic ShMOLLI myocardial T1-mapping for improved robustness to partial-volume effects and applications in tachyarrhythmias” Journal of Cardiovascular Magnetic Resonance 2015, 17:77. View full text.
  7. VM Ferreira, SK Piechnik, MD Robson, S. Neubauer, TD Karamitsos. “Myocardial tissue characterization by MRI: Novel applications of T1 and T2 mapping.” Journal of Thoracic Imaging.  2014 May; 29(3):147-54. View full text.
  8. VM Ferreira, SK Piechnik, S Firoozan, TD Karamitsos, S Neubauer. Acute chest pain and massive left ventricular hypertrophy in a 38 year-old man. Heart. 2014 Feb;100 (4):347. View full text.
  9. VM Ferreira; CJ Holloway; SK Piechnik; TD Karamitsos; S Neubauer. Is it really fat? Ask a T1-map. European Heart Journal – Cardiovascular Imaging. 2013 Nov;14(11):1060. View full text.
  10. SK Piechnik; VM Ferreira; E Dall’Armellina; LE Cochlin; A Greiser; S Neubauer; MD Robson. Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold. Journal Cardiovascular Magnetic Resonance 2010, 12: 69. View full text.
  11. Piechnik SK; Ferreira VM; Lewandowski AJ; Ntusi NAB; Banerjee R; Holloway C; Hofman MBM; Sado DM; Maestrini V; White S; Lazdam M; Karamitsos T; Moon JC; Neubauer S; Leeson P; Robson MD. Normal variation of magnetic resonance T1 relaxation times in the human population at 1.5T using ShMOLLI. Journal of Cardiovascular Magnetic Resonance 2013, 15:13. View full text.
  12. E. Dall’Armellina; V. Ferreira; R. Kharbanda; B. Prendergast; S. Piechnik; M. Robson; J. Francis; R. Choudhury; S. Neubauer. Diagnostic value of pre-contrast T1 mapping characterization in patients with acute and chronic myocardial infarction. JACC Cardiovasc Imaging. 2013 Jun;6(6):739-42. View full text.
  13. E Dall’Armellina; S Piechnik; V Ferreira; QL Si, M Robson; JM Francis; F Cuculi; RK. Kharbanda; AP Banning; RP Choudhury; TD Karamitsos; S Neubauer. Cardiovascular magnetic resonance by non contrast T1 mapping allows assessment of severity of injury in acute myocardial infarction. Journal of Cardiovascular Magnetic Resonance 2012;14:15. View full text.
  14. Dall’Armellina E, Ferreira VM, Neubauer S. “T1-mapping in ischemic heart disease” in Cardiac Magnetic Resonance. Current Cardiovascular Imaging Reports (2014) 7:9262. View full text.
  15. Yilmaz A, Ferreira V, Klingel K, Kandolf R, Neubauer S, Sechtem U. Role of cardiovascular magnetic resonance imaging (CMR) in the diagnosis of acute and chronic myocarditis. Heart Failure Reviews. 2012:1-14. View full text.

 

 

 

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